目次

Table of Contents

I. Introduction

II. Worldwide Market Overview
　1. Market Overview
　2. Worldwide Market Structure
　3. Worldwide Market Size and Growth

III. Major Product Development Opportunities
A. Reagent Kits and Test Systems/Panels
B. Instrumentation
C. Computers, Software and Automation
D. Auxiliary Products

IV. Design Criteria for Decentralized Testing Products

V. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies
　1. Marketing Approaches
　2. Product Complexity
　3. Customer Preference
　4. Established Suppliers
　5. Emerging Suppliers
　6. Major Types of Distributors
　7. Market Segmentation Factor

VI. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

VII. Worldwide Market and Technology Overview
A. Cancer Statistics and Etiology
　1. Breast Cancer
　2. Lung Cancer
　3. Colon and Rectum Cancer
　4. Prostate Cancer
　5. Stomach Cancer
　6. Leukemia
　7. Lymphoma
　8. Oral Cancer
　9. Skin Cancer
　10. Uterine Cancer
　11. Ovarian Cancer
　12. Bladder Cancer
B. Major Current And Emerging Cancer Diagnostic Tests
　1. Introduction
　2. Tumor Marker Classification
　3. ACTH
　4. Alpha-Fetoprotein (AFP)
　5. Beta-2 Microglobulin
　6. CA 15-3/27.29
　7. CA 19-9
　8. CA-125
　9. Calcitonin
　10. Carcinoembrionic Antigen (CEA)
　11. Estrogen and Progesterone Receptors
　12. Ferritin
　13. Gastrin
　14. Human Chorionic Gonadotropin (HCG)
　15. Insulin
　16. NSE
　17. Occult Blood
　18. PAP Smear/HPV
　19. Prostatic Acid Phosphatase (PAP)
　20. Prostate-Specific Antigen (PSA)
　21. Squamous Cell Carcinoma Antigen (SCC)
　22. T and B Lymphocytes
　23. TdT
　24. Thyroglobulin
　25. Tissue Polypeptide Antigen (TPA)
　26. Biochemical Tumor Markers
　　　- ADA
　　　- B-Protein
　　　- PNP
　　　- 5'-Nucleotidase
　27. Oncogenes
　　　- Abl/abl-bcr
　　　- AIB1
　　　- BCL-2
　　　- BRCA1
　　　- CD44
　　　- C-fos
　　　- C-myb
　　　- C-myc
　　　- CYP-17
　　　- Erb-B
　　　- HPC1
　　　- N-myc
　　　- P40
　　　- P51
　　　- P53
　　　- PIK3CA
　　　- PTI-1
　　　- Ras
　　　- Reg
　　　- Sis
　　　- Src
　28. Polypeptide Growth Factors
　　　- Basic Fibroblast Growth Factor
　　　- Beta-TGF
　　　- Cachectin (TNT)
　　　- Calmodulin
　　　- ECFR
　　　- Nerve Growth Factor (NGF)
　　　- Epidermal Growth Factor (EGF)
　　　- Ornithine Decarboxylase
　　　- Transferrin
　　　- Transforming Growth Factor-Alpha
　29. Ectopic Hormones
　30. Colony Stimulating Factors
　31. Lymphokines
　　　- Alpha-Interferon
　　　- B Cell Growth Factors
　　　- B Cell Growth Factor (BCGF)
　　　- Gamma-Interferon
　　　- Interleukin-1 (IL-1)
　　　- Macrophage Activating Factor
　32. Immunohistochemical Stains
　33. Emerging Tumor Markers
　　　- N-Acetylglucosamine
　　　- Actin
　　　- Alpha-Actin
　　　- Antineuronal Antibodies
　　　- 7B2
　　　- B72.3
　　　- Bax
　　　- BCD-F9
　　　- BLCA-4
　　　- Blood Group Antigens A,B,H
　　　- CA 50
　　　- CA 72-4/TAG-72
　　　- CA 195
　　　- CA-242
　　　- CA-549
　　　- CAM 26
　　　- CAR-3
　　　- Cathepsin-D
　　　- Chromogranin A and B
　　　- Cluster 1 Antigen
　　　- Cluster-5/5A Antigen
　　　- CTA
　　　- CU18
　　　- DR-70
　　　- DU-PAN-2
　　　- Endometrial Bleeding Associated Factor
　　　- Endostatin
　　　- Epithelial Membrane Antigen
　　　- Feulgen Hydrolysis
　　　- Fibronectin
　　　- FSH
　　　- (1->3)-L-fucosyltransferase
　　　- Gastrin-Releasing Peptide (GRP)
　　　- GDCFP-15
　　　- Glucagon
　　　- Glycoamines
　　　- H23
　　　- Her-2
　　　- Human Carcinoma Antigen
　　　- HPA
　　　- HSP27
　　　- Intermediate Filaments
　　　- Cytokeratins/CK18/Cyfra 21-1
　　　- Desmin
　　　- Gliofibrillary Acid Protein
　　　- Neurofilaments
　　　- Vimentin
　　　- KA 93
　　　- Kinases
　　　- KP16D3
　　　- LAI
　　　- Leukocyte Common Antigen
　　　- Lewis Antigens
　　　- Lysophosphatidic Acid (LPA)
　　　- Ma 695/Ma 552
　　　- MABDF3
　　　- MAG
　　　- ME1
　　　- Minactivin
　　　- MN/CA9
　　　- MSA
　　　- Mucin Cancer Antigen (MCA)
　　　- Multiple Tumor Suppressor 1
　　　- Myosin
　　　- NEA-130
　　　- NMP22
　　　- OA-519
　　　- Opiod Peptides
　　　- P-glycoprotein
　　　- Pancreatic Oncofetal Antigen (POA)
　　　- Placental Lactogen
　　　- PR92
　　　- Proliferative Index, Ki-67
　　　- Px
　　　- RB Inactivation/Deletion
　　　- Ret
　　　- SCCL 175
　　　- Selectin
　　　- Sialic Acid
　　　- Sialyl SSEA-1/SLX
　　　- SN10
　　　- Somatostatin
　　　- TA-90
　　　- TABA
　　　- Tachykinin
　　　- TAG 12
　　　- TPS
　　　- Troponin
　　　- Tubulin
　　　- VCAM
　　　- VEGF
　　　- Villen
C. Instrumentation Review And Market Needs
D. Current and Emerging Technologies
　1. Molecular Diagnostics
　　a. Technology Overview b. Amplification Methods c. Sequencing
　　d. Microarrays/Biochips
　2. Monoclonal and Polyclonal Antibodies
　3. Immunoassays
　　a. Technological Principle
　　b. Radioimmunoassay (RIA)
　　c. Enzyme Immunoassays (EIA)
　　　- Overview
　　　- ELISA
　　　- Immunofiltration
　　　- Particle-Membrane Capture Immunoassay
　　　- Enzyme Amplification
　　d. Fluorescent Immunoassays e. Luminescence
　　　- Chemiluminescence
　　　- Bioluminescence f. Latex Agglutination
　　g. Immunoprecipitation h. Affinity Chromatographu
　　e. Liposome Flow-Injection Immunoassay
　4. Chromosome Analysis
　　a. Chronic Myelogenous Leukemia (CML)
　　b. Acute Myeloid Leukemia (AML)
　　c. Acute Lymphoblastic Leukemia (ALL)
　　d. Malignant Lymphomas Lymphoid Malignancies e. Chronic Lymphocytic Leukemia (CLL)
　　f. Solid Cancers
　　g. Chromosomal Translocation and Oncogenes
　5. Artificial Intelligence
　6. Flow Cytometry
　7. Two Dimensional Gel Electrophoresis (2-DGE)
　8. Biosensors
　9. Competing/Complementing Technologies a. CT
　　b. MRI
　　c. NMR
　　d. PET
　　e. Photonics Spectroscopy
E. Personal Testing

VIII. France
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares

IX. Germany
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares

X. Italy
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares

XI. Japan
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares

XII. Spain
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares

XIII. U.K.
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares

XIV. U.S.A.
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares

XV. Competitive Profiles
　　　- Abbott
　　　- Affymetrix
　　　- Beckman Coulter/Danaher
　　　- Becton Dickinson
　　　- bioMerieux
　　　- Bio-Rad
　　　- Cepheid
　　　- Diamedix
　　　- DiaSorin
　　　- Eiken Chemical
　　　- Elitech Group
　　　- Enzo Biochem
　　　- Fujirebio
　　　- Grifols
　　　- GSK Biologicals
　　　- Hologic
　　　- Leica Biosystems
　　　- Lonza
　　　- Ortho-Clinical Diagnostics
　　　- PerkinElmer
　　　- Qiagen
　　　- Roche
　　　- Scienion
　　　- Sequenom
　　　- SeraCare
　　　- Siemens Healthineers
　　　- Takara Bio
　　　- Thermo Fisher
　　　- Wako

XVI. Appendix: Major Universities and Research Centers Developing Cancer Diagnostic Technology and Applications

List of Tables
Tumor Marker Classification
Major Companies Developing or Marketing
ACTH Tests
Major Companies Developing or Marketing
AFP Tests
Major Companies Developing or Marketing
Beta-2 Microglobulin Tests
Major Companies Developing or Marketing
CA 15-3/27.29 Tests
Major Companies Developing or Marketing
CA 19-9 Tests
Major Companies Developing or Marketing
CA 125 Tests
Major Companies Developing or Marketing
Calcitonin Tests
Major Companies Developing or Marketing
CEA Tests
Major Companies Developing or Marketing
Estrogen Receptor Tests
Major Companies Developing or Marketing
Progesterone Receptor Tests
Major Companies Developing or Marketing
Ferritin Tests
Major Companies Developing or Marketing
Gastrin Tests
Major Companies Developing or Marketing
HCG Tests
Major Companies Developing or Marketing
Insulin Tests
Major Companies Developing or Marketing
NSE Tests
Major Companies Developing or Marketing
Occult Blood Tests
Major Companies Developing or Marketing
PAP Smear/HPV Tests
Major Companies Developing or Marketing
PAP Tests
Major Companies Developing or Marketing
PSA Tests
Major Companies Developing or Marketing
Lymphocyte Subclassification Tests
Biochemical Markers Potential Applications
In Cancer Diagnosis
Oncogenes Potential Applications
In Cancer Diagnosis
Major Companies Developing or Marketing
Oncogene Tests
Growth Factors Potential Applications
In Cancer Diagnosis
Colony Stimulating Factors Potential
Applications in Cancer Diagnosis
Lymphokines Potential Applications In Cancer Diagnosis
Immunohistochemical Stains Potential
Applications in Cancer Diagnosis
Executive Summary Table: France, Total Cancer
Diagnostic Test Volume and Sales Forecast by Market Segment
France, Laboratories Performing Tumor
Marker Tests by Market Segment
France, Hospital Laboratories Performing
Tumor Marker Tests by Bed Size
France, Commercial/Private Laboratories
Performing Tumor Markers by Annual Test Volume
France, Total Tumor Marker Test Volume
Forecast by Market Segment
France, All Market Segments Major Tumor
Marker Test Volume Forecast
France, Hospital Laboratories Major Tumor
Marker Test Volume Forecast by Test
France, Commercial/Private Laboratories
Marker Test Volume Forecast
France, Total Tumor Marker Sales Major Tumor
Forecast by Market Segment
France, All Market Segments Major Tumor
Marker Sales Forecast by Test
France, Hospital Laboratories Major Tumor
Marker Sales Forecast by Test
France, Commercial/Private Laboratories Cancer
Diagnostics Market Forecast by Test
France, Total Tumor Marker Sales by Major Suppliers
France, AFP Testing Market Diagnostics
Sales by Major Supplier
France, CA 15-3 Testing Market Diagnostics
Sales by Major Supplier
France, CA 19-9 Testing Market Diagnostics
Sales by Major Supplier
France, CA 125 Testing Market Diagnostics
Sales by Major Supplier
France, CEA Testing Market Diagnostics
Sales by Major Supplier
France, NSE Testing Market Diagnostics
Sales by Major Supplier
France, PAP Testing Market Diagnostics
Sales by Major Supplier
France, PSA Testing Market Diagnostics
Sales by Major Supplier
Executive Summary Table: Germany, Total Tumor Marker Test Volume and Sales Forecast By Market Segment
Germany, Laboratories Performing Tumor
Marker Tests by Market Segment
Germany, Hospital Laboratories Performing
Tumor Marker Tests by Bed Size
Germany, Commercial/Private Laboratories
Performing Tumor Markers by Annual
Test Volume
Germany, Total Tumor Marker Test Volume
Forecast by Market Segment
Germany, All Market Segments, Major Tumor
Marker Test Volume Forecast
Germany, Hospital Laboratories, Major
Tumor Marker Test Volume Forecast by Test
Germany, Commercial/Private Laboratories
Major Tumor Marker Test Volume Forecast
Germany, Physician Offices/Group
Practices Major Tumor Marker
Test Volume Forecast
Germany, Total Tumor Marker Sales
Forecast by Market Segment
Germany, All Market Segments Major Tumor
Marker Sales Forecast by Test
Germany, Hospital Laboratories, Major Tumor
Marker Sales Forecast by Test
Germany, Commercial/Private Laboratories
Major Tumor Marker Sales Forecast by Test
Germany, Physician Offices/Group Practices
Major Tumor Marker Sales Forecast by Test
Germany, Total Tumor Marker Sales by Major Supplier
Germany, AFP Testing Market Diagnostics
Sales by Major Supplier
Germany CA 15-3/27.29 Testing Market
Diagnostics Sales by Major Supplier
Germany CA 19-9 Testing Market Diagnostics
Sales by Major Supplier
Germany, CA 125 Testing Market Diagnostics
Sales by Major Supplier
Germany, CEA Testing Market Diagnostics
Sales by Major Supplier
Germany, PSA Testing Market Diagnostics
Sales by Major Supplier
Executive Summary Table: Italy, Total Tumor Marker Test Volume and Diagnostics Sales Forecast by Market Segment
Italy, Laboratories Performing Tumor
Marker Tests by Market Segment
Italy, Hospital Laboratories Performing
Tumor Marker Tests by Bed Size
Italy, Commercial/Private Laboratories Performing Tumor Markers by Annual Test Volume
Italy, Total Tumor Marker Test Volume
Forecast by Market Segment
Italy, All Market Segments Major Cancer
Diagnostic Test Volume Forecast
Italy, Hospital Laboratories Major Tumor
Marker Test Volume Forecast
Italy, Commercial/Private Laboratories
Major Tumor Marker Test Volume Forecast
Italy, Total Tumor Marker Test Market
Forecast by Market Segment
Italy, All Market Segments Major Tumor
Marker Sales Forecast by Test
Italy, Hospital Laboratories Major
Tumor Marker Forecast by Test
Italy, Commercial/Private Laboratories
Major Tumor Marker Sales Forecast by Test
Italy, Total Tumor Markers
Sales by Major Suppliers
Italy, AFP Testing Market Diagnostics
Sales by Major Supplier
Italy, CEA Testing Market Diagnostics
Sales by Major Supplier
Italy, PSA Testing Market Diagnostics
Sales by Major Supplier
Executive Summary Table: Japan, Total Tumor Marker Test Volume and Sales Forecast by Market Segment
Japan, Laboratories Performing Tumor
Marker Tests by Market Segment
Japan, Hospital Laboratories Performing
Tumor Marker Tests by Bed Size
Japan, Commercial/Private Laboratories
Performing Tumor Marker Tests by Annual Test Volume
Japan, Total Tumor Marker Testing Volume
Forecast by Market Segment
Japan, All Market Segments Major Tumor
Marker Test Volume Forecast
Japan, Hospital Laboratories Major Tumor
Marker Test Volume Forecast by Test
Japan, Commercial/Private Laboratories Major
Tumor Marker Test Volume Forecast
Japan, Total Tumor Marker Sales
Forecast by Market Segment
Japan, All Market Segments Major Tumor
Marker Sales Forecast by Test
Japan, Hospital Laboratories Major Tumor
Marker Sales Forecast by Test
Japan, Commercial/Private Laboratories Major
Tumor Marker Sales Forecast by Test
Japan, Total Tumor Marker
Sales by Major Suppliers
Japan, AFP Testing Market Diagnostics
Sales by Major Supplier
Japan, CA 15-3/27.29 Testing Market
Diagnostics Sales by Major Supplier
Japan, CA 19-9 Testing Market Diagnostics
Sales by Major Supplier
Japan, CA 125 Testing Market Diagnostics
Sales by Major Supplier
Japan, Calcitonin Testing Market Diagnostics
Sales by Major Supplier
Japan, PAP Testing Market Diagnostics
Sales by Major Supplier
Japan, PSA Testing Market Diagnostics
Sales by Major Supplier
Executive Summary Table: Spain, Total Tumor Marker Test Volume and Sales Forecast by Market Segment
Spain, Laboratories Performing Tumor
Marker Tests by Market Segment
Spain, Hospital Laboratories Performing
Tumor Marker Tests by Bed Size
Spain, Commercial/Private Laboratories
Performing Tumor Markers by
Annual Test Volume
Spain, Total Tumor Marker Test Volume
Forecast by Market Segment
Spain, All Market Segment Major Cancer
Diagnostic Test Volume Forecast
Spain, Hospital Laboratories Major Cancer
Diagnostic Test Volume Forecast by Test
Spain, Commercial/Private Laboratories
Major Tumor Marker Test Volume Forecast
Spain, Total Tumor Marker Sales
Forecast by Market Segment
Spain, All Market Segments Major Tumor
Marker Sales Forecast by Test
Spain, Hospital Laboratories Major Tumor
Marker Sales Forecast by Test
Spain, Commercial/Private Laboratories Major
Tumor Marker Sales Forecast by Test
Segment
Spain, Total Tumor Marker Sales by Major Suppliers
Spain, AFP Testing Market Diagnostics
Sales by Major Supplier
Spain, CA 15-3/27.29 Testing Market
Diagnostics Sales by Major Supplier
Spain, 19-9 Testing Market Diagnostics
Sales by Major Supplier
Spain, CA 125 Testing Market Diagnostics
Sales by Major Supplier
Spain, CEA Testing Market Diagnostics
Sales by Major Supplier
Spain, PSA Testing Market Diagnostics
Sales by Major Supplier
Executive Summary Table: U.K., Total Tumor Marker Test Volume and Sales Forecast by Market Segment
U.K., Laboratories Performing Tumor
Marker Tests by Market Segment
U.K., Hospital Laboratories Performing
Tumor Marker Tests by Bed Size
U.K., Commercial/Private Laboratories Performing Tumor Marker Tests by Annual Test Volume
U.K., Total Tumor Marker Testing Volume
Forecast by Market Segment
U.K., All Market Segments Major
Tumor Marker Test Volume Forecast
U.K., Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
U.K., Commercial/Private Laboratories
Major Tumor Marker Test Volume Forecast
U.K., Total Tumor Marker Sales
Forecast by Market Segment
U.K., All Market Segments Major
Tumor Marker Sales Forecast by Test
U.K., Hospital Laboratories Major
Tumor Marker Sales Forecast by Test
U.K., Commercial/Private Laboratories
Major Tumor Marker Sales Forecast by Test
U.K., Total Tumor Marker Sales and Market Shares Forecast
U.K., CEA Testing Market Diagnostics
Sales by Major Supplier
U.K., PSA Testing Market Diagnostics
Sales by Major Supplier
Executive Summary Table: U.S., Total Tumor
Marker Test Volume and Sales Forecast by Market Segment
U.S., Laboratories Performing Tumor
Marker Tests by Market Segment
U.S., Hospital Laboratories Performing
Tumor Marker Tests by Bed Size
U.S., Commercial/Private Laboratories
Performing Tumor Marker Tests by Annual Test Volume
U.S., Physician Office Laboratories
Performing Tumor Marker Tests by Practice Size
U.S., Total Tumor Marker Test Volume
Forecast by Market Segment
U.S., All Market Segments Major
Tumor Marker Test Volume Forecast
U.S., Hospital Laboratories Major Tumor
Marker Test Volume Forecast by Test
U.S., Commercial/Private Laboratories
Major Tumor Marker Test Volume Forecast
U.S., Physician Offices/Group Practices
Major Tumor Marker Test Volume Forecast
U.S., Cancer Clinics Major Tumor
Marker Test Volume Forecast by Test
U.S., Total Tumor Marker Sales
Forecast by Market Segment
U.S., All Market Segment Major Tumor
Marker Sales Forecast by Test
U.S., Hospital Laboratories Major Tumor
Marker Sales Forecast by Test
U.S., Commercial/Private Laboratories
Major Tumor Marker Sales Forecast by Test
U.S., Physician Offices/Group Practices
Major Tumor Marker Sales Forecast by Test
U.S., Cancer Clinics Major Tumor
Marker Sales Forecast by Test
U.S., Total Tumor Marker Sales by Major Supplier
U.S., ACTH Testing Market Diagnostics
Sales by Major Supplier
U.S., AFP Testing Market Diagnostics
Sales by Major Supplier
U.S., Beta-2 Migroblolulin Testing Market Diagnostics Sales by Major Supplier
U.S., CA 15-3/27.29 Testing Market
Diagnostics Sales by Major Supplier
U.S., CA 19-9 Testing Market Diagnostics
Sales by Major Supplier
U.S., CA 125 Testing Market Diagnostics
Sales by Major Supplier
U.S., CEA Testing Market Diagnostics
Sales by Major Supplier
U.S., Ferritin Testing Market
Diagnostics Sales by Major Supplier
U.S., HCG Testing Market
Diagnostics Sales by Major Supplier
U.S., Insulin Testing Market
Diagnostics Sales by Major Supplier
U.S., Parathyroid Hormone Testing Market
Diagnostics Sales by Major Supplier
U.S., PSA Testing Market Diagnostics
Sales by Major Supplier