目次

Table of Contents

List of Tables

List of Figures
Introduction
Global Markets Direct Report Coverage
Down Syndrome - Overview
Down Syndrome - Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Down Syndrome - Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Down Syndrome - Companies Involved in Therapeutics Development
AC Immune SA
Aelis Farma SAS
Alzheon Inc
Annovis Bio Inc
Avanti Biosciences Inc
Balance Therapeutics Inc
Eisai Co Ltd
Elixirgen Therapeutics Inc
F. Hoffmann-La Roche Ltd
Felicitex Therapeutics Inc
KinoPharma Inc
Laminar Pharmaceuticals SA
Les Laboratoires Servier SAS
ManRos Therapeutics
NeuroCircuit Therapeutics Inc
NeuroNascent Inc
Perha Pharmaceuticals SAS
Prothena Corp Plc
SanBio Co Ltd
Down Syndrome - Drug Profiles
ABI-02 - Drug Profile
Product Description
Mechanism Of Action
ACI-24 - Drug Profile
Product Description
Mechanism Of Action
History of Events
AEF-0217 - Drug Profile
Product Description
Mechanism Of Action
History of Events
ANVS-405 - Drug Profile
Product Description
Mechanism Of Action
ARN-23746 - Drug Profile
Product Description
Mechanism Of Action
buntanetap - Drug Profile
Product Description
Mechanism Of Action
History of Events
D-217 - Drug Profile
Product Description
Mechanism Of Action
DYR-219 - Drug Profile
Product Description
Mechanism Of Action
FX-8546 - Drug Profile
Product Description
Mechanism Of Action
Gene Therapy to Activate ZSCAN4 for Chromosomal Disorders - Drug Profile
Product Description
Mechanism Of Action
History of Events
KPO-1143 - Drug Profile
Product Description
Mechanism Of Action
History of Events
LAM-226 - Drug Profile
Product Description
Mechanism Of Action
LCTB-21 - Drug Profile
Product Description
Mechanism Of Action
lecanemab - Drug Profile
Product Description
Mechanism Of Action
History of Events
minocycline hydrochloride - Drug Profile
Product Description
Mechanism Of Action
NNI-351 - Drug Profile
Product Description
Mechanism Of Action
pegaspargase - Drug Profile
Product Description
Mechanism Of Action
History of Events
pentylenetetrazol - Drug Profile
Product Description
Mechanism Of Action
History of Events
RO-4938581 - Drug Profile
Product Description
Mechanism Of Action
Small Molecule for Alzheimer's Disease and Down Syndrome - Drug Profile
Product Description
Mechanism Of Action
Small Molecule to Inhibit DYRK1A for Alzheimer's Disease and Down Syndrome - Drug Profile
Product Description
Mechanism Of Action
Small Molecule to Inhibit DYRK1A for Down Syndrome - Drug Profile
Product Description
Mechanism Of Action
History of Events
Small Molecules for Down Syndrome - Drug Profile
Product Description
Mechanism Of Action
Small Molecules to Inhibit OLIG2 for Down Syndrome - Drug Profile
Product Description
Mechanism Of Action
valiltramiprosate - Drug Profile
Product Description
Mechanism Of Action
History of Events
Down Syndrome - Dormant Projects
Down Syndrome - Discontinued Products
Down Syndrome - Product Development Milestones
Featured News & Press Releases
Jan 05, 2022: Annovis Bio announces official unique name buntanetap for lead candidate ANVS401
May 13, 2021: Annovis Bio files for FDA Orphan Drug Designation for ANVS401 for the treatment of Alzheimer's disease in persons with Down syndrome
Apr 29, 2021: Annovis Bio to study potential of ANVS401 to normalize brain development in Down syndrome
Mar 16, 2021: AC Immune announces new clinical results in Down syndrome and plans for future development of anti-Amyloid-Beta vaccine
Mar 15, 2021: BioArctic and Eisai presented latest data regarding lecanemab at AD/PD 2021
Mar 11, 2021: Annovis Bio signs GMP manufacturing agreement to support planned late-stage studies
Mar 05, 2021: Latest lecanemab data to be presented at the AD/PD congress
Feb 02, 2021: Annovis bio's lead candidate ANVS401 improves cognitive and functional outcomes in stroke mice study
Dec 15, 2020: Annovis Bio showcases its unique approach to Alzheimer's at the New York Academy of Sciences
Sep 29, 2020: Annovis Bio demonstrates improved axonal transport in nerve cells and brain of down syndrome mice, an animal model of Alzheimer's disease
Jul 23, 2020: AC Immune to present advances in two of the company's world leading programs at the upcoming Alzheimer's Association International Conference
Jul 10, 2020: Discovery of a novel drug candidate to develop effective treatments for brain disorders
Jul 11, 2019: AC Immune hosts KOL event and reports initial interim clinical data for ACI-24 vaccine to treat Alzheimer's Disease-like symptoms in subjects with Down Syndrome
Aug 20, 2018: AC Immune announces important clinical milestones for ACI-24 vaccine in alzheimers disease and down syndrome
Sep 12, 2017: AC Immune Completes Recruitment For Low-Dose Cohort In World's First Clinical Trial For Anti-Abeta Vaccine Targeting Alzheimer's Disease-Like Characteristics In Individuals With Down Syndrome
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List of Tables
Number of Products under Development for Down Syndrome, 2022
Number of Products under Development by Companies, 2022
Number of Products under Development by Universities/Institutes, 2022
Products under Development by Companies, 2022
Products under Development by Universities/Institutes, 2022
Number of Products by Stage and Target, 2022
Number of Products by Stage and Mechanism of Action, 2022
Number of Products by Stage and Route of Administration, 2022
Number of Products by Stage and Molecule Type, 2022
Down Syndrome - Pipeline by AC Immune SA, 2022
Down Syndrome - Pipeline by Aelis Farma SAS, 2022
Down Syndrome - Pipeline by Alzheon Inc, 2022
Down Syndrome - Pipeline by Annovis Bio Inc, 2022
Down Syndrome - Pipeline by Avanti Biosciences Inc, 2022
Down Syndrome - Pipeline by Balance Therapeutics Inc, 2022
Down Syndrome - Pipeline by Eisai Co Ltd, 2022
Down Syndrome - Pipeline by Elixirgen Therapeutics Inc, 2022
Down Syndrome - Pipeline by F. Hoffmann-La Roche Ltd, 2022
Down Syndrome - Pipeline by Felicitex Therapeutics Inc, 2022
Down Syndrome - Pipeline by KinoPharma Inc, 2022
Down Syndrome - Pipeline by Laminar Pharmaceuticals SA, 2022
Down Syndrome - Pipeline by Les Laboratoires Servier SAS, 2022
Down Syndrome - Pipeline by ManRos Therapeutics, 2022
Down Syndrome - Pipeline by NeuroCircuit Therapeutics Inc, 2022
Down Syndrome - Pipeline by NeuroNascent Inc, 2022
Down Syndrome - Pipeline by Perha Pharmaceuticals SAS, 2022
Down Syndrome - Pipeline by Prothena Corp Plc, 2022
Down Syndrome - Pipeline by SanBio Co Ltd, 2022
Down Syndrome - Dormant Projects, 2022
Down Syndrome - Discontinued Products, 2022

List of Figures
Number of Products under Development for Down Syndrome, 2022
Number of Products under Development by Companies, 2022
Number of Products under Development by Universities/Institutes, 2022
Number of Products by Targets, 2022
Number of Products by Stage and Targets, 2022
Number of Products by Mechanism of Actions, 2022
Number of Products by Stage and Mechanism of Actions, 2022
Number of Products by Routes of Administration, 2022
Number of Products by Stage and Routes of Administration, 2022
Number of Products by Molecule Types, 2022
Number of Products by Stage and Top 10 Molecule Types, 2022