オピオイド中毒は、一定期間、オピオイドを常用した後に発症します。オピオイドを長期間使用すると、脳内の神経が損傷し、細胞が内因性オピオイド(エンドルフィンという天然の鎮痛薬)の産生を停止してしまうことがあります。これは、痛みを隠すためのエンドルフィンがないため、体が痛みを止められなくなることにつながります。痛みを抑える神経細胞が変性することで、外部からの供給源としてアヘンに身体的に依存するようになります。兆候や症状としては、全身不安の増大、多幸感、精神病、うつ病、高血圧、食欲低下、身体の興奮、睡眠障害、骨の痛みなどがあります。素因には、年齢、薬物乱用の個人歴、薬物乱用の家族歴、タバコ依存症、精神的ストレスなどがあります。
目次
Table of Contents
List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Opium (Opioid) Addiction - Overview
Opium (Opioid) Addiction - Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Opium (Opioid) Addiction - Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Opium (Opioid) Addiction - Companies Involved in Therapeutics Development
Opium (Opioid) Addiction - Drug Profiles
Opium (Opioid) Addiction - Dormant Projects
Opium (Opioid) Addiction - Discontinued Products
Opium (Opioid) Addiction - Product Development Milestones
Featured News & Press Releases
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products under Development for Opium (Opioid) Addiction, 2022
Number of Products under Development by Companies, 2022
Number of Products under Development by Companies, 2022 (Contd..1)
Number of Products under Development by Companies, 2022 (Contd..2)
Number of Products under Development by Universities/Institutes, 2022
Products under Development by Companies, 2022
Products under Development by Companies, 2022 (Contd..1)
Products under Development by Companies, 2022 (Contd..2)
Products under Development by Companies, 2022 (Contd..3)
Products under Development by Universities/Institutes, 2022
Number of Products by Stage and Target, 2022
Number of Products by Stage and Target, 2022 (Contd..1)
Number of Products by Stage and Mechanism of Action, 2022
Number of Products by Stage and Mechanism of Action, 2022 (Contd..1)
Number of Products by Stage and Route of Administration, 2022
Number of Products by Stage and Molecule Type, 2022
Opium (Opioid) Addiction - Dormant Projects, 2022
Opium (Opioid) Addiction - Dormant Projects, 2022 (Contd..1)
Opium (Opioid) Addiction - Discontinued Products, 2022
List of Figures
Number of Products under Development for Opium (Opioid) Addiction, 2022
Number of Products under Development by Companies, 2022
Number of Products under Development by Universities/Institutes, 2022
Number of Products by Top 10 Targets, 2022
Number of Products by Stage and Top 10 Targets, 2022
Number of Products by Top 10 Mechanism of Actions, 2022
Number of Products by Stage and Top 10 Mechanism of Actions, 2022
Number of Products by Top 10 Routes of Administration, 2022
Number of Products by Stage and Top 10 Routes of Administration, 2022
Number of Products by Molecule Types, 2022
Number of Products by Stage and Molecule Types, 2022