世界の酵素的 DNA 合成市場は 2022 年に 2 億 5,342 万ドルと評価され、2028 年には 21 億 1,000 万ドルになると予想されます。酵素的 DNA 合成には、従来の化学技術の代わりに酵素を使用して DNA 鎖を生成することが含まれます。酵素の一種である DNA ポリメラーゼは、ヌクレオチド間のホスホジエステル結合の形成を触媒し、新しい DNA 鎖を生成することによって、このプロセスにおいて極めて重要な役割を果たします。酵素合成法は、自然の DNA 複製に非常に似ており、TdT などの酵素を利用するため、DNA ポリメラーゼとは異なり、テンプレートの必要がありません。このプロセスには、個々のヌクレオチドをつなぎ合わせて二本鎖 DNA 分子を形成することが含まれます。ヌクレオチドのカップリングとターミネーターの除去は化学合成に似ていますが、酵素合成は次のヌクレオチド付加ラウンドの準備を整えます。その非毒性の性質にもかかわらず、酵素的方法は現在、オリゴヌクレオチドの製造において化学的方法によって達成される精度にわずかに及びません。
酵素による DNA 合成の生産と需要は、いくつかの動向によって形成されると予想されます。ワークフローの自動化がさらに普及し、効率が向上し、手作業の必要性が減ると考えられます。継続的な研究開発努力によって、より効率的な酵素と技術の開発につながり、プロセスの精度と拡張性がさらに向上すると予想されます。さらに、酵素による DNA 合成は、遺伝子編集やゲノム工学への応用のために、CRISPR/Cas9 などの他の分子生物学技術と統合される可能性があります。酵素的 DNA 合成市場は、2023 年から 2028 年にかけて 42.43% の CAGR で成長する見込みです。
目次
Table of Contents
1. Executive Summary
2. Introduction
2.1 Enzymatic DNA Synthesis: An Overview
2.1.1 Two Widely Used Methods of Enzymatic DNA Assembly
2.2 Enzymatic DNA Synthesis: An Overview
2.2.1 Enzymatic DNA Synthesis Segmentation
3. Global Market Analysis
3.1 Global Enzymatic DNA Synthesis Market: An Analysis
3.1.1 Global Enzymatic DNA Synthesis Market: An Overview
3.1.2 Global Enzymatic DNA Synthesis Market by Value
3.1.3 Global Enzymatic DNA Synthesis Market by Product Type (DNA Library Synthesis and Custom DNA Synthesis)
3.1.4 Global Enzymatic DNA Synthesis Market by Technology (PCR, CRISPR, SOLA and Others)
3.1.5 Global Enzymatic DNA Synthesis Market by Application (Synthetic Biology, Therapeutic Antibodies, Genetic Engineering, Vaccine Design, and Other)
3.1.6 Global Enzymatic DNA Synthesis Market by End Users (Biotech and Pharmaceutical Companies, Academic and Research Institutes, Diagnostic Laboratories, and Others)
3.1.7 Global Enzymatic DNA Synthesis Market by Region (North America, Europe, Asia Pacific, Latin America and Middle East & Africa)
3.2 Global Enzymatic DNA Synthesis Market: Product Type Analysis
3.2.1 Global Enzymatic DNA Synthesis Market by Product Type: An Overview
3.2.2 Global DNA Library Enzymatic DNA Synthesis Market by Value
3.2.3 Global Custom Enzymatic DNA Synthesis Market by Value
3.3 Global Enzymatic DNA Synthesis Market: Technology Analysis
3.3.1 Global Enzymatic DNA Synthesis Market by Technology: An Overview
3.3.2 Global PCR Enzymatic DNA Synthesis Market by Value
3.3.3 Global CRISPR Enzymatic DNA Synthesis Market by Value
3.3.4 Global SOLA Enzymatic DNA Synthesis Market by Value
3.3.5 Global Other Enzymatic DNA Synthesis Technologies Market by Value
3.4 Global Enzymatic DNA Synthesis Market: Application Analysis
3.4.1 Global Enzymatic DNA Synthesis Market by Application: An Overview
3.4.2 Global Synthetic Biology Enzymatic DNA Synthesis Market by Value
3.4.3 Global Therapeutic Antibodies Enzymatic DNA Synthesis Market by Value
3.4.4 Global Vaccine Design Enzymatic DNA Synthesis Market by Value
3.4.5 Global Genetic Engineering Enzymatic DNA Synthesis Market by Value
3.4.6 Global Other Enzymatic DNA Synthesis Applications Market by Value
3.5 Global Enzymatic DNA Synthesis Market: End User Analysis
3.5.1 Global Enzymatic DNA Synthesis Market by End User: An Overview
3.5.2 Global Biotech and Pharmaceutical Companies Enzymatic DNA Synthesis Market by Value
3.5.3 Global Academic and Research Institutes Enzymatic DNA Synthesis Market by Value
3.5.4 Global Diagnostic Laboratories Enzymatic DNA Synthesis Market by Value
3.5.5 Global Other Enzymatic DNA Synthesis End Users Market by Value
4. Regional Market Analysis
4.1 North America Enzymatic DNA Synthesis Market: An Analysis
4.1.1 North America Enzymatic DNA Synthesis Market: An Overview
4.1.2 North America Enzymatic DNA Synthesis Market by Value
4.1.3 North America Enzymatic DNA Synthesis Market by Region (The US, Canada and Mexico)
4.1.4 The US Enzymatic DNA Synthesis Market by Value
4.1.5 Canada Enzymatic DNA Synthesis Market by Value
4.1.6 Mexico Enzymatic DNA Synthesis Market by Value
4.2 Europe Enzymatic DNA Synthesis Market: An Analysis
4.2.1 Europe Enzymatic DNA Synthesis Market: An Overview
4.2.2 Europe Enzymatic DNA Synthesis Market by Value
4.2.3 Europe Enzymatic DNA Synthesis Market by Region (Germany, Uk, France, Italy, Spain and Rest of Europe)
4.2.4 Germany Enzymatic DNA Synthesis Market by Value
4.2.5 United Kingdom Enzymatic DNA Synthesis Market by Value
4.2.6 France Enzymatic DNA Synthesis Market by Value
4.2.7 Italy Enzymatic DNA Synthesis Market by Value
4.2.8 Spain Enzymatic DNA Synthesis Market by Value
4.2.9 Rest of Europe Enzymatic DNA Synthesis Market by Value
4.3 Asia Pacific Enzymatic DNA Synthesis Market: An Analysis
4.3.1 Asia Pacific Enzymatic DNA Synthesis Market: An Overview
4.3.2 Asia Pacific Enzymatic DNA Synthesis Market by Value
4.3.3 Asia Pacific Enzymatic DNA Synthesis Market by Region (China, Japan, India, South Korea nd Rest of Asia Pacific)
4.3.4 China Enzymatic DNA Synthesis Market by Value
4.3.5 Japan Enzymatic DNA Synthesis Market by Value
4.3.6 India Enzymatic DNA Synthesis Market by Value
4.3.7 South Korea Enzymatic DNA Synthesis Market by Value
4.3.8 Rest of Asia Pacific Enzymatic DNA Synthesis Market by Value
4.4 Latin America Enzymatic DNA Synthesis Market: An Analysis
4.4.1 Latin America Enzymatic DNA Synthesis Market: An Overview
4.4.2 Latin America Enzymatic DNA Synthesis Market by Value
4.5 Middle East & Africa Enzymatic DNA Synthesis Market: An Analysis
4.5.1 Middle East & Africa Enzymatic DNA Synthesis Market: An Overview
4.5.2 Middle East & Africa Enzymatic DNA Synthesis Market by Value
5. Impact of Covid-19
5.1 Impact of COVID-19
5.1.1 Impact of COVID-19 on Global Enzymatic DNA Synthesis Market
5.1.2 Post-COVID Scenario
6. Market Dynamics
6.1 Growth Drivers
6.1.1 Rising Prevalence of Genetic Disorders
6.1.2 Advancements in Enzymes and Technologies
6.1.3 Customization and Precision
6.1.4 Growing Applications in Synthetic Biology
6.1.5 Increasing Demand for DNA
6.2 Challenges
6.2.1 Stringent Government Regulations and Guidelines
6.2.2 High Costs and Complex Procedures
6.3 Market Trends
6.3.1 Emerging Fields
6.3.2 CRISPR-Cas9 Integration
6.3.3 Cell-Free Synthetic Biology
7. Competitive Landscape
7.1 Global Enzymatic DNA Synthesis Market Players: Competitive landscape
7.2 Global Enzymatic DNA Synthesis Market Players: Recent Funding Rounds
8. Company Profiles
8.1 Telesis Bio, Inc.
8.1.1 Business Overview
8.1.2 Revenue by Category
8.1.3 Business Strategies
8.2 Twist Bioscience Corporation
8.2.1 Business Overview
8.2.2 Revenue by Product
8.2.3 Business Strategies
8.3 Genscript Biotech Corporation
8.3.1 Business Overview
8.3.2 Operating Segments
8.3.3 Business Strategies
8.4 Evonetix
8.4.1 Business Overview
8.4.2 Business Strategies
8.5 Ansa Biotechnologies, Inc.
8.5.1 Business Overview
8.5.2 Business Strategies
8.6 Camena Bioscience
8.6.1 Business Overview
8.6.2 Business Strategies
8.7 Molecular Assemblies
8.7.1 Business Overview
8.7.2 Business Strategies
8.8 DNA Script
8.8.1 Business Overview
8.8.2 Business Strategies
8.9 Touchlight
8.9.1 Business Overview
8.9.2 Business Strategies
8.10 Kern Systems
8.10.1 Business Overview
8.10.2 Business Strategies
List of Figures
Figure 1: Advantages of Enzymatic DNA Synthesis
Figure 2: Two Widely Used Methods of Enzymatic DNA Assembly
Figure 3: Enzymatic DNA Synthesis Segmentation
Figure 4: Global Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 5: Global Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Billion)
Figure 6: Global Enzymatic DNA Synthesis Market by Product Type; 2022 (Percentage, %)
Figure 7: Global Enzymatic DNA Synthesis Market by Technology; 2022 (Percentage, %)
Figure 8: Global Enzymatic DNA Synthesis Market by Application; 2022 (Percentage, %)
Figure 9: Global Enzymatic DNA Synthesis Market by End Users; 2022 (Percentage, %)
Figure 10: Global Enzymatic DNA Synthesis Market by Region; 2022 (Percentage, %)
Figure 11: Global DNA Library Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 12: Global DNA Library Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 13: Global Custom Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 14: Global Custom Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 15: Global PCR Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 16: Global PCR Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 17: Global CRISPR Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 18: Global CRISPR Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 19: Global SOLA Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 20: Global SOLA Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 21: Global Other Enzymatic DNA Synthesis Technologies Market by Value; 2018-2022 (US$ Million)
Figure 22: Global Other Enzymatic DNA Synthesis Technologies Market by Value; 2023-2028 (US$ Million)
Figure 23: Global Synthetic Biology Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 24: Global Synthetic Biology Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 25: Global Therapeutic Antibodies Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 26: Global Therapeutic Antibodies Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 27: Global Vaccine Design Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 28: Global Vaccine Design Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 29: Global Genetic Engineering Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 30: Global Genetic Engineering Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 31: Global Other Enzymatic DNA Synthesis Applications Market by Value; 2018-2022 (US$ Million)
Figure 32: Global Other Enzymatic DNA Synthesis Applications Market by Value; 2023-2028 (US$ Million)
Figure 33: Global Biotech and Pharmaceutical Companies Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 34: Global Biotech and Pharmaceutical Companies Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 35: Global Academic and Research Institutes Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 36: Global Academic and Research Institutes Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 37: Global Diagnostic Laboratories Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 38: Global Diagnostic Laboratories Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 39: Global Other Enzymatic DNA Synthesis End Users Automation Market by Value; 2018-2022 (US$ Million)
Figure 40: Global Other Enzymatic DNA Synthesis End Users Market by Value; 2023-2028 (US$ Million)
Figure 41: North America Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 42: North America Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 43: North America Enzymatic DNA Synthesis Market by Region; 2022 (Percentage, %)
Figure 44: The US Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 45: The US Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 46: Canada Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 47: Canada Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 48: Mexico Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 49: Mexico Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 50: Europe Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 51: Europe Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 52: Europe Enzymatic DNA Synthesis Market by Region; 2022 (Percentage, %)
Figure 53: Germany Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 54: Germany Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 55: United Kingdom Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 56: United Kingdom Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 57: France Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 58: France Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 59: Italy Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 60: Italy Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 61: Spain Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 62: Spain Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 63: Rest of Europe Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 64: Rest of Europe Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 65: Asia Pacific Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 66: Asia Pacific Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 67: Asia Pacific Enzymatic DNA Synthesis Market by Region; 2022 (Percentage, %)
Figure 68: China Enzymatic DNA Synthesis Market by Value, 2018-2022 (US$ Million)
Figure 69: China Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 70: Japan Enzymatic DNA Synthesis Market by Value, 2018-2022 (US$ Million)
Figure 71: Japan Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 72: India Enzymatic DNA Synthesis Market by Value, 2018-2022 (US$ Million)
Figure 73: India Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 74: South Korea Enzymatic DNA Synthesis Market by Value, 2018-2022 (US$ Million)
Figure 75: South Korea Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 76: Rest of Asia Pacific Enzymatic DNA Synthesis Market by Value, 2018-2022 (US$ Million)
Figure 77: Rest of Asia Pacific Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 78: Latin America Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 79: Latin America Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 80: Middle East & Africa Enzymatic DNA Synthesis Market by Value; 2018-2022 (US$ Million)
Figure 81: Middle East & Africa Enzymatic DNA Synthesis Market by Value; 2023-2028 (US$ Million)
Figure 82: The US New Cancer Cases; 2019-2023 (Thousand)
Figure 83: Telesis Bio, Inc. Revenue by Category; 2022 (Percentage, %)
Figure 84: Twist Bioscience Corporation Revenue by Product; 2022 (Percentage, %)
Figure 85: Genscript Biotech Corporation Revenue by Segments; 2022 (Percentage, %)
Table 1: Global Enzymatic DNA Synthesis Market Players: Recent Funding Rounds
