筋萎縮性側索硬化症（ALS）は、運動ニューロン系で最も一般的な変性疾患です。筋萎縮とは、筋繊維の萎縮を意味し、筋繊維は対応する前角細胞の変性に伴って脱神経されることから、その病態生理に基づいて命名されました。側索硬化症は、脊髄の側柱に見られる上部運動ニューロン（UMN）の軸索が変性し、繊維状のアストロサイトに置き換わる（グリオーシス）ことによって起こる変化を指します。症状としては、呼吸困難、嚥下困難、首の筋力低下による頭部下垂、筋けいれん、言葉が遅い、異常な話し方（不明瞭）、声変わり、嗄声、体重減少などが挙げられます。
目次
Table of Contents
List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Amyotrophic Lateral Sclerosis - Overview
Amyotrophic Lateral Sclerosis - Therapeutics Development
Pipeline Overview
Pipeline by Companies
Pipeline by Universities/Institutes
Products under Development by Companies
Products under Development by Universities/Institutes
Amyotrophic Lateral Sclerosis - Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Amyotrophic Lateral Sclerosis - Companies Involved in Therapeutics Development
Amyotrophic Lateral Sclerosis - Drug Profiles
Amyotrophic Lateral Sclerosis - Dormant Projects
Amyotrophic Lateral Sclerosis - Discontinued Products
Amyotrophic Lateral Sclerosis - Product Development Milestones
Featured News & Press Releases
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products under Development for Amyotrophic Lateral Sclerosis, 2022
Number of Products under Development by Companies, 2022
Number of Products under Development by Universities/Institutes, 2022
Products under Development by Companies, 2022
Products under Development by Universities/Institutes, 2022
Number of Products by Stage and Target, 2022
Number of Products by Stage and Mechanism of Action, 2022
Number of Products by Stage and Route of Administration, 2022
Number of Products by Stage and Molecule Type, 2022
Amyotrophic Lateral Sclerosis - Dormant Projects, 2022
Amyotrophic Lateral Sclerosis - Discontinued Products, 2022
Amyotrophic Lateral Sclerosis - Discontinued Products, 2022 (Contd..1)
List of Figures
Number of Products under Development for Amyotrophic Lateral Sclerosis, 2022
Number of Products under Development by Companies, 2022
Number of Products under Development by Universities/Institutes, 2022
Number of Products by Top 10 Targets, 2022
Number of Products by Stage and Top 10 Targets, 2022
Number of Products by Top 10 Mechanism of Actions, 2022
Number of Products by Stage and Top 10 Mechanism of Actions, 2022
Number of Products by Top 10 Routes of Administration, 2022
Number of Products by Stage and Top 10 Routes of Administration, 2022
Number of Products by Top 10 Molecule Types, 2022
Number of Products by Stage and Top 10 Molecule Types, 2022
